Virginia Creeper is a vine that is commonly found climbing up the sides of trees or other structures. It is often confused with Poison Ivy as the two plants share many similarities. Both are vines that climb up trees. Both have compound leaves. Both are found in the same native range. However, Virginia Creeper does not contain urushiol, the chemical that causes a rash which is found in Poison Ivy. This makes it perfectly safe to handle for most people, though there are a small number of people who are allergic to it and may develop a slight rash. The easiest way to tell the two vines apart is to look at the leaves. Where Poison Ivy always has three leaves, Virginia Creeper always has five.